miR-21 Targets ASPP2 to Inhibit Apoptosis via CHOP-Mediated Signaling in Helicobacter pylori-Infected Gastric Cancer Cells

Figure 8

H. pylori-induced miR-21-mediated ASPP2 suppression confers resistance to apoptosis through inhibition of ASPP2/CHOP-mediated transcription of Noxa and Bak and suppression of Bcl-2 in the GC cells.