Journal of Toxicology / 2024 / Article / Tab 2 / Research Article
Assessment of Acute and Chronic Toxicity in Wistar Rats (Rattus norvegicus ) and New Zealand Rabbits (Oryctolagus cuniculus) of an Enriched Polyphenol Extract Obtained from Caesalpinia spinosa Table 2 Absolute and relative weight of liver, left kidney, left adrenal, and spleen in rats and rabbits.
Sex Group N Liver Kidney L Adrenal L Spleen AW (g) RW (%) AW (g) RW (%) AW (g) RW (%) AW (g) RW (%) Rats Females Test 3 9.31 ± 0.73 3.51 ± 0.08 0.99 ± 0.02 0.38 ± 0.02 0.0483 ± 0.0036 0.0182 ± 0.0012 0.56 ± 0.10 0.21 ± 0.02 Control 5 8.24 ± 0.61 3.29 ± 0.31 0.91 ± 0.10 0.36 ± 0.04 0.0370 ± 0.042 0.0148 ± 0.0023 0.49 ± 0.10 0.19 ± 0.03 value0.07 0.22 0.15 0.63 0.008 0.06 0.36 0.49 Males Test 3 16.63 ± 1.88 3.05 ± 0.29 1.55 ± 0.23 0.28 ± 0.03 0.0338 ± 0.0038 0.0062 ± 0.006 0.81 ± 0.12 0.15 ± 0.01 Control 5 17.01 ± 1.61 3.35 ± 0.38 1.58 ± 0.07 0.31 ± 0.03 0.0336 ± 0.0083 0.0065 ± 0.0011 0.80 ± 0.12 0.16 ± 0.02 value0.77 0.29 0.88 0.29 0.97 0.72 0.87 0.57 Rabbits Test 7 84.13 ± 11.31 1.925 ± 0.357 9.66 ± 0.83 0.221 ± 0.031 0.256 ± 0.069 0.006 ± 0.002 2.31 ± 0.55 0.052 ± 0.010 Control 5 91.16 ± 13.90 1.801 ± 0.088 10.85 ± 1.11 0.216 ± 0.015 0.302 ± 0.067 0.006 ± 0.001 2.43 ± 0.56 0.048 ± 0.010 value0.36 0.41 0.06 0.74 0.28 0.8 0.71 0.52