Controlled Release of Mesenchymal Stem Cell-Conditioned Media from a Microsphere/Gel-Based Drug Delivery System for Wound Healing of Tympanic Membrane Perforations

Figure 5

Representative images of TM postsacrifice. (a) Pristine TM from contralateral ear with no manipulations or treatment; (b) healed perforation and normal physiology characterized by sagging TM and presence of dried blood; (c) healed perforation but abnormal physiology; (d) residual perforation. The white arrow pinpoints the location of the perforation. TMP, tympanic membrane perforation. Scale bar = 60 mm.

(a)

(b)

(c)

(d)