Research Article

Comparison of Oropharyngeal Microbiota from Children with Asthma and Cystic Fibrosis

Table 1

Demographic description of the cohort.

ControlAsthmaCF

n622757
Male/female28/3421/646/11
Age in years (min–max)10.10 (8–12)10.00 (8–12)10.61 (6–12)
FEV1 in L (min–max)1.99 (1.15–3.18)1.83 (1.26–2.35)1.92 (0.88–3.34)
FEV1 z-score ± SD−0.44 ± 1.08−0.43 ± 0.79−1.78 ± 1.37
FVC in L (min–max)2.36 (1.44–3.87)2.25 (1.53–3.34)2.40 (1.04–3.86)
FVC z-score ± SD−0.17 ± 0.790.12 ± 0.93−1.42 ± 1.32
% antibiotic use within 4 weeks prior to sampling1.613.7045.61

FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity. z-scores were calculated following the Global Lung Function Initiative (GLI) equation from 2012 [44].