Comparison of Oropharyngeal Microbiota from Children with Asthma and Cystic Fibrosis

Table 1

Demographic description of the cohort.

	Control	Asthma	CF
n	62	27	57
Male/female	28/34	21/6	46/11
Age in years (min–max)	10.10 (8–12)	10.00 (8–12)	10.61 (6–12)
FEV1 in L (min–max)	1.99 (1.15–3.18)	1.83 (1.26–2.35)	1.92 (0.88–3.34)
FEV1 z-score ± SD	−0.44 ± 1.08	−0.43 ± 0.79	−1.78 ± 1.37
FVC in L (min–max)	2.36 (1.44–3.87)	2.25 (1.53–3.34)	2.40 (1.04–3.86)
FVC z-score ± SD	−0.17 ± 0.79	0.12 ± 0.93	−1.42 ± 1.32
% antibiotic use within 4 weeks prior to sampling	1.61	3.70	45.61

FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity. z-scores were calculated following the Global Lung Function Initiative (GLI) equation from 2012 [44].