Aqueous Humor Apolipoprotein Concentration and Severity of Diabetic Retinopathy in Type 2 Diabetes
Table 2
Concentration levels (mean ± SD (median; interquartile ranges (IQR) 25–75); ng/ml) of apolipoproteins in the AH diabetic patients without and with different stages of DR.
Non-apparent DR ()
Mild/moderate NPDR ()
Advanced NPDR/PDR ()
1
2
Apo AI
(235; 93-801)
(543; 288-1572)
(2494; 1328-3393)
<0.0001
0.0015
Apo AII
(104; 40.1-293)
(221; 106-477)
(870; 320-1092)
<0.0001
0.0058
Apo CI
(42; 22-108)
(80; 46-129)
(210; 126-275)
<0.0001
0.005
Apo CIII
(2.2; 1.0-5.8)
(4.6; 1.9-11.3)
(26.3; 8.3-40.8)
0.00027
0.0098
Apo D
(29; 17-50)
(39;26-74)
(114; 84-132)
0.00011
0.0046
Apo E
(79; 41-127)
(82; 57-188)
(226;155-296)
0.0023
0.0326
Apo H
(484; 275-943)
(1238; 569-2434)
(3177; 1761-6906)
<0.0001
0.0015
Apo J
(564; 302-805)
(465; 366-1468)
(1548; 1010-1925)
0.00526
0.1280
Abbreviations: AH: aqueous humor; 1: value between nonapparent DR and advanced NPDR/PDR. 2: value between mild/moderate NPDR and advanced NPDR/PDR. value remained significant after application of the Holm correction.
