Research Article
Aquaporin-4 Autoantibody Detection by ELISA: A Retrospective Characterization of a Commonly Used Assay
| | NMOSD | Other | High positive (range) | Moderate positive (range) | | | | |
| CSF testing reported | | | | Pleocytosis (cells/mm3) | 4 (12–282) | 4 (0–106) | 2 (5–246) | Protein (mg/dL) | 4 (41–106) | 4 (27–48) | 2 (32–122) | Oligoclonal bands, | 5 | 4 | 3 | CSF unique, | 2 (1–3) | 2 (1–3) | 2 (3–4) | Matched, | 4 | 1 | 1 | None | 1 | 1 | 0 | Autoimmune markers/immune dysfunction | | | | SSA/B | 2 | N/R | N/R | RF | 1 | N/R | N/R | ANA | 1 | N/R | N/R | Myasthenia | N/R | 1 | N/R | Hypogammaglobulinemia | N/R | N/R | 1 |
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N/R: not reported. “Matched” refers to identical oligoclonal band detection in both serum and CSF.
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