Review Article

The Application of tDCS to Treat Pain and Psychocognitive Symptoms in Cancer Patients: A Scoping Review

Table 1

Characteristics of included studies.

First author, yearCountrySample sizeAge range and/or mean (SD)Cancer typeStudy design

Gao et al., 2022 [47]ChinaN = 72
tDCS group, n = 36 (29 M, 7 F)
CG, n = 36 (31 M, 5 F)
tDCS group: 52.5 ± 8.6
CG: 53.1 ± 8.2
Oral cancerRS

Gaynor et al., 2020 [45]USAN = 16 (F)40–65 yearsBreast cancerPS

Knotkova et al., 2014 [42]USAN = 1 (F)55 yearsBreast cancerSC

Nguyen et al., 2016 [39]FranceN = 1 (M)80 yearsBladder cancerSC

Stamenkovic et al., 2020 [46]SerbiaN = 55
tDCS group, n = 27; (16 M, 11 F)
Sham group, n = 28; (23 M, 5 F)
tDCS group: 61.44 ± 7.98
Sham group: 61.89 ± 5.79
Lung cancerRCT

Hu et al., 2016 [34]USAN = 98
tDCS group, n = 5 (4 M, 1 F)
CG, n = 93 (retrospective data)
62.6 ± 5Head and neck cancerPS

Kamal et al., 2022 [43]EgyptN = 60 (F)
tDCS group, n = 30
Sham group, n = 30
tDCS group: 48.4 ± 6.6
Sham group: 50.4 ± 5.7
Breast cancerRCT

Ibrahim et al., 2018 [44]EgyptN = 40
tDCS group, n = 20 (n.a.)
Sham group, n = 20 (n.a.)
tDCS group: 58.9 ± 5.6
Sham group: 56.85 ± 9.16
HCCRCT

Mirski et al., 2015 [40]PolandN = 1 (F)45 yearsMeningiomaSC

Silva et al., 2007 [41]BrazilN = 1 (F)65 yearsPancreatic cancerSC

Notes. tDCS = transcranial direct current stimulation; SD = standard deviation; USA = United States of America; CG = control group; M = male; F = female; n.a. = not applicable; HCC = hepatocellular carcinoma; RS = retrospective study; PS = pilot study; SC = single case study; and RCT = randomized controlled trial.