Research Article

A Retrospective Cohort Study Evaluating the Safety and Efficacy of Sequential versus Concurrent Intrapleural Instillation of Tissue Plasminogen Activator and DNase for Pleural Infection

Table 2

Clinical characteristics of pleural infection ().

Hospital-acquired infection19 (14.1)
Right-sided pleural effusion82 (60.7)
Size of pleural effusion based on radiographic imaging
 Small (<1/3 hemithorax)11 (8.2)
 Moderate (1/3 to 2/3 hemithorax)62 (45.9)
 Large (>2/3 hemithorax)62 (45.9)
CT or ultrasonographic evidence of pleural loculations124 (91.9)
Pleural fluid appearance
 Serous or turbid70 (51.9)
 Hemoserous38 (28.1)
 Purulent27 (20.0)
Gram stain/culture-positive pleural fluid54 (40.0)
Gram stain/culture-positive pleural fluid or blood62 (45.9)
Bacteremia10 (7.4)
Pleural fluid characteristics
 Lactate dehydrogenase (IU/L)2225 (982-4313)
 Glucose (mmol/L)3.0 (0.6-4.9)
Peripheral leukocyte count (×109/L)15.2 (10.7-19.6)
C-reactive protein (mg/L)197 (129-288)
RAPID score3 (2-4)
 Low risk (0-2)50 (37.0)
 Medium risk (3, 4)56 (41.5)
 High risk (5–7)29 (21.5)

Data are presented in number (percentage) and median (interquartile range) for categorical and continuous variables, respectively. CT: computed tomography.