Research Article
PPAR-γ Activation Alleviates Osteoarthritis through Both the Nrf2/NLRP3 and PGC-1α/Δψm Pathways by Inhibiting Pyroptosis
Table 1
Histochemical assessment of rat articular cartilage changes.
| Grade | S-O staining |
| 0 | Uniform staining throughout articular cartilage | 1 | Loss of staining in superficial zone of hyaline cartilage <50% the length of the condyle or plateau | 2 | Loss of staining in superficial zone of hyaline cartilage ≥50% the length of the condyle or plateau | 3 | Loss of staining in the upper 2/3’s of hyaline cartilage <50% the length of the condyle or plateau | 4 | Loss of staining in the upper 2/3’s hyaline cartilage ≥50% the length of the condyle or plateau | 5 | Loss of staining in all the hyaline cartilage <50% the length of the condyle or plateau | 6 | Loss of staining in all the hyaline cartilage ≥50% the length of the condyle or plateau |
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