Research Article
Buspirone Induces Weight Loss and Normalization of Blood Pressure via the Stimulation of PPARδ Dependent Energy Producing Pathway in Spontaneously Hypertensive Rats
Figure 7
Immunohistochemistry for angiotensin II type 1 receptor (AT1R) and vascular cell adhesion molecule 1 (VCAM1) in aorta slides from SHRs. Expressions for AT1R and VCAM1 were elevated in 8w untreated group compared to 4w normal group; however, the increased expressions were decreased in all buspirone treated groups (a and b). The results are expressed as mean ± standard error of the mean (). Values were statistically analyzed using the unpaired t-test to compare two groups, and to compare means of three or more groups was used one-way ANOVA test and followed by Bonferroni’s multiple comparisons test. All experiments were repeated over three times. ****.
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