Research Article
Appraisal of the Possible Role of PPARγ Upregulation by CLA of Probiotic Pediococcus pentosaceus GS4 in Colon Cancer Mitigation
Figure 2
The c9t11-CLA and BADGE can bind to human PPARγ: The hPPARγ protein was retrieved from protein data bank and molecular docking was performed using AutoDock followed by LigPlot analysis. Binding energy was used in order to rank structures in each cluster. (a) PyMOL view of molecular interaction between c9t11-CLA and hPPARγ. (b) 2D docking complex of c9t11-CLA with the amino acid residues of hPPARγ. (c) PyMOL view of molecular interaction between BADGE and hPPARγ. (d) 2D docking complex of BADGE with the amino acid residues of hPPARγ. (e) The merge view of 2D docking complex of c9t11-CLA and BADGE with the amino acid residues of hPPARγ protein.
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