Exploring the Diagnostic Dilemma of Indeterminate Pulmonary Nodules in Patients with Primary Sarcoma of Bone
Table 1
Descriptive data of the initial, preoperative CT chest findings in patients presenting with a primary sarcoma of the bone without known metastatic disease at the time of diagnosis.
All patients
Patients presenting with indeterminant nodules on initial/preoperative CT chest
Patients presenting without nodules on initial/preoperative CT chest
value
N
117
73
44
Age (years)
48.6 (16–81)
50 (19–81)
46.2 (16–76)
0.281
Follow-up (months)
38.2 (2–192)
40.9 (2–192)
33.8 (2–107)
0.432
Gender
Male
69
41 (56.2%)
28 (63.6%)
0.426
Female
48
32 (43.8%)
16 (36.4%)
Smoking history
Never
70
42 (57.5%)
28 (63.6%)
0.543
+ Smoking history
36
25 (34.2%)
11 (25.0%)
Unknown
11
6 (8.2%)
5 (11.4%)
Diagnosis
Osteosarcoma
36
24 (32.9%)
12 (27.3%)
0.886
Chondrosarcoma
49
30 (41.1%)
19 (43.2%)
Ewing sarcoma
8
4 (5.5%)
4 (9.1%)
Chordoma
4
2 (2.7%)
2 (4.5%)
Others
20
13 (17.8%)
7 (15.9%)
Grade
Low
8
5 (6.8%)
3 (6.8%)
0.995
High
109
68 (93.2%)
41 (93.2%)
Anatomic location
Upper extremity
21
10 (13.7%)
11 (25.0%)
0.476
Lower extremity
48
32 (43.8%)
16 (36.4%)
Spine/chest wall
13
8 (11.0%)
5 (11.4%)
Pelvis
35
23 (31.5%)
12 (27.3%)
Progressed to metastatic disease
Yes
49
30 (41.1%)
19 (43.2%)
0.825
No
68
43 (58.9%)
25 (56.8%)
Time to metastatic disease (months)
16.7 (2–86)
11.6 (2–40)
24.6 (2–86)
0.008
value: comparison of patients presenting with indeterminant nodules vs. presenting without nodules for each considered variable, performed with Chi-square and Mann–Whitney U tests.
