Electrophysiological Changes of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes during Acute Hypoxia and Reoxygenation

<div>Gene expression of apoptosis-related BAX and BCL2, cellular stress-related HSPA1A and MYH7, angiogenic VEGFA and glycolysis-related SLC2A1, and PKM isoforms 1 and 2 in hiPSC-CMs after hypoxia (H: hypoxia; C<sub>H</sub>: control for H) and reoxygenation (HR: hypoxia; C<sub>HR</sub>: control for HR). There were significant intrasample and intercell line variation in the expression of the genes, and the differences in the expressions of the genes were subtle and not statistically significant.</div>

Stem Cells International

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Figure 7

Figure 7: Electrophysiological Changes of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes during Acute Hypoxia and Reoxygenation 