Research Article

11C-Labeled Pictilisib (GDC-0941) as a Molecular Tracer Targeting Phosphatidylinositol 3-Kinase (PI3K) for Breast Cancer Imaging

Table 1

IC50 values of pictilisib, GDCI, and GDCM against cells.

CompoundsMCF-7MDA-MB-231
IC50 (μmol/L)95% CIIC50 (μmol/L)95% CI

Pictilisib7.145.56–9.1719.5714.40–26.60
GDCI6.915.02–9.5116.0015.06–17.00
GDCM73.2628.64–187.4130.871.57–406.8