Research Article

A Comparative Study of Two-Compartment Exchange Models for Dynamic Contrast-Enhanced MRI in Characterizing Uterine Cervical Carcinoma

Table 3

Comparison of model parameters between cervix carcinoma and normal cervix tissue.

Fp (mL/min/100 mL)Vp (mL/100 mL)Ve (mL/100 mL)PS (mL/min/100 mL)

AATH-normal cervix44.57 ± 23.231.27 ± 1.2532.15 ± 14.3210.40 ± 6.43
AATH- cervix cancer34.13 ± 15.152.55 ± 2.3017.03 ± 10.808.88 ± 4.28
<0.001a<0.001a<0.05a>0.05a
AUC0.670.750.850.56

SC-normal cervix19.51 ± 15.966.00 ± 7.6529.95 ± 17.3311.14 ± 7.18
SC-cervix cancer18.48 ± 7.316.80 ± 4.2419.21 ± 20.056.21 ± 4.40
>0.05b<0.001a<0.001a<0.001a
AUC0.500.640.750.75

DP-normal cervix16.06 ± 21.224.90 ± 3.2431.88 ± 18.419.67 ± 5.62
DP-cervix cancer14.83 ± 5.234.38 ± 3.0616.05 ± 13.348.13 ± 3.96
<0.01a>0.05b<0.001a<0.05a
AUC0.600.540.830.58

AUC, area under the ROC curve. aComparison was performed by the Mann–Whitney U test. bComparison was performed by the independent t test.