Effect of Doxycycline on Survival in Abdominal Aortic Aneurysms in a Mouse Model

Figure 4

Ex vivo results from LA-ICP-MS. A–I are unpublished images from a previous study [21]. # indicates the vessel lumen, indicates the thrombus area (both nonenhancing organized thrombus and not fully organized thrombus), and § indicates an area where the cryosection tore during preparation. A, D, and G correspond to the unstained frozen sections. B, E, and H show the spatial distribution of gadolinium (from gadofosveset) in aortic aneurysms assessed by LA-ICP-MS. Brighter colors in the color bars on the right (red and yellow) correspond to higher gadolinium concentrations with the highest measured gadolinium concentration being 120 μg/g (red color). C, F, and I correspond to albumin-specific staining with minor C and confluent (F–I) immunopositive fluorescent areas of albumin.