Acute Exercise-Induced Response of Monocyte Subtypes in Chronic Heart and Renal Failure
Table 2
Distribution of monocyte subsets and levels of inflammatory proteins at baseline.
HS ()
CKD ()
CHF ()
value
Leukocytes
WBC count (/mL)
7.17 ± 1.60
5.76 ± 1.45
8.24 ± 1.82
<0.001
WBC formula (% of leukocytes)
%neutrophils
65.1 ± 10.6
63.1 ± 7.8
59.8 ± 9.7
0.24
%lymphocytes
24.8 ± 8.7
24.2 ± 6.8
27.5 ± 8.3
0.38
%monocytes
6.28 ± 1.24
6.16 ± 1.35
7.72 ± 1.88
<0.05
Monocytes
Monocyte count (cells/L)
450 ± 128
352 ± 103
628 ± 159
<0.001
Monocyte subsets (% of monocytes)
%Mon1
88.09 ± 4.73
88.48 ± 4.27
87.34 ± 3.54
0.67
%Mon2
4.51 ± 2.05
3.56 ± 1.69
4.74 ± 2.46
0.18
%Mon3
7.39 ± 3.17
7.95 ± 3.61
7.92 ± 2.19
0.83
Monocyte subsets (cells/L)
Mon1
395.2 ± 107
311.6 ± 93.8
550.3 ± 143.9
<0.001
Mon2
20.7 ± 13.5
13.1 ± 8.7
29.3 ± 17.1
<0.01
Mon3
34.1 ± 20.9
27.3 ± 13.9
49.3 ± 17.3
<0.01
Inflammatory cytokines
MCP-1 (pg/mL)
330 ± 163
446 ± 95∗
420 ± 119∗
0.028
IL-6 (pg/mL)
1.17 ± 1.72
1.63 ± 1.43
1.41 ± 1.33
0.69
Data are mean ± SD. value for comparison of groups (ANOVA). ∗Different from HS, . Different from CKD, . MCP-1: monocyte chemoattractant protein-1; IL-6: interleukin-6.
