Elevated Serum IgG4 Defines Specific Clinical Phenotype of Rheumatoid Arthritis

Figure 2

Histopathological features of synovium of 2 RA patients (400x). Images of the left column were from one RA patient with higher synovial IgG4-positive plasma cells and the right column from another RA patient with lower synovial IgG4-positive plasma cells. (a, b) H&E staining. (c, d) IgG4 immunohistochemistry staining. (e, f) Masson’s trichrome staining. (g, h) CD3 immunohistochemistry staining. (i, j) CD20 immunohistochemistry staining. (k, l) CD38 immunohistochemistry staining.

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