Oxidative and/or Inflammatory Thrust Induced by Silver Nanoparticles in Rabbits: Effect of Vitamin E or NSAID Administration on Semen Parameters

Table 2

Estimated marginal means and standard error of principal component (PC) scores in rabbits treated with a saline solution (control group), AgNPs (AgNP group), or lipopolysaccharides (LPS group).

PC	Group^1			value
	Control	AgNPs	LPS
				Group	Time	Interaction
Motility				<0.001	<0.001	<0.001
Volume				0.443	0.012	0.006
Antioxidants				<0.001	<0.001	<0.001
Oxidative metabolites				<0.001	<0.001	<0.001
Redox reaction				<0.001	<0.001	<0.001
TNF-α and IL-8				<0.001	<0.001	<0.001
IL-6				<0.001	<0.001	<0.001

Values in the same row not sharing the same subscript are significantly different at (Sidak correction). PC: principal component; TNF-α: tumor necrosis factor alpha; IL: interleukin. ¹Control group, treated with 2 ml of 0.9% saline solution; AgNP group, treated with 5 mM AgNP solution; LPS group, inoculated with 50 g/kg b.w. of E. coli LPS.