The Severity of CVB3-Induced Myocarditis Can Be Improved by Blocking the Orchestration of NLRP3 and Th17 in Balb/c Mice

Figure 4

Correlation analysis of NLRP3 inflammasome and Th17 cells. (a) Correlation analysis between NLRP3 (mRNA level in the heart) and Th17 cells (proportion in the spleen, left) or IL-17 expression (IOD score detected by IHC in heart, right). (b) Correlation analysis between NLRP3 (mRNA level in the spleen) and Th17 cells (proportion in the spleen, left) or IL-17 expression (IOD score detected by IHC in the heart, right). (c) Correlation analysis between NLRP3 (protein level in the heart) and Th17 cells (proportion in the spleen, left) or IL-17 expression (IOD score detected by IHC in the heart, right). P: value; R: Spearman .

(a)

(b)

(c)