The Severity of CVB3-Induced Myocarditis Can Be Improved by Blocking the Orchestration of NLRP3 and Th17 in Balb/c Mice

<table class="table-group" id="tab5"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left">Groups</td><td class="align_center">CVB3</td><td class="align_center">Anti-IL-1<i>β</i> (I.P. 100 <i>μ</i>g/time)</td><td class="align_center">Saline (equal volume)</td><td class="align_center">ISO (I.P. 100 <i>μ</i>g/time)</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left">Control</td><td class="align_center">−</td><td class="align_center">−</td><td class="align_center">+</td><td class="align_center">−</td></tr><tr><td class="align_left">Anti-IL-1<i>β</i></td><td class="align_center">+</td><td class="align_center">+</td><td class="align_center">+</td><td class="align_center">−</td></tr><tr><td class="align_left">Saline</td><td class="align_center">+</td><td class="align_center">−</td><td class="align_center">+</td><td class="align_center">−</td></tr><tr><td class="align_left">ISO</td><td class="align_center">+</td><td class="align_center">−</td><td class="align_center">+</td><td class="align_center">+</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Groups of VMC mice treated with anti-IL-1<i>β</i> antibody.</div>

Mediators of Inflammation

tab5

Table 5

Table 5: The Severity of CVB3-Induced Myocarditis Can Be Improved by Blocking the Orchestration of NLRP3 and Th17 in Balb/c Mice 