Vagal Nerve Stimulation-Modulation of the Anti-Inflammatory Response and Clinical Outcome in Psoriatic Arthritis or Ankylosing Spondylitis

Table 2

Result—psoriatic arthritis.

	Baseline	20 min	value	Day 2	value	Day 5	value	Overall value
Cardiometric data
Cardiac vagal tone (LVS)	5.73 (0.72)	5.68 (0.72)	0.892	5.49 (0.72)	0.531	4.69 (0.71)	0.007	0.023
Heart rate (bpm)			0.017		0.077		0.307	0.002
Systolic BP (mmHg)			0.872		0.150		0.141	0.031
Diastolic BP (mmHg)			0.310		0.710		0.173	0.255
Disease activity
DAS28-CRP	2.54 (0.16)	-	-	2.53(0.16)	0.876	2.45 (0.16)	0.162	0.309
ASDAS	2.22 (0.20)	-	-	2.07 (0.20)	0.063	2.03 (0.20)	0.012	0.033
CRP (mg/L)	3.23 (0.84)	-	-	2.72 (0.84)	0.043	2.59 (0.84)	0.001	0.004
Cytokines
IFN-γ (pg/L)	4.96 (0.92)	-	-	5.19 (0.12)	0.735	6.27 (0.89)	0.101	0.089
IL-8 (pg/mL)	3.41 (0.30)	-	-	3.72 (0.30)	0.324	3.99 (0.30)	0.061	0.172
IL-10 (pg/mL)	0.29 (0.05)	-	-	0.26 (0.04)	0.281	0.30 (0.05)	0.482	0.193
TNF-α (pg/mL)	1.65 (0.17)	-	-	1.69 (0.17)	0.476	1.81 (0.17)	0.005	0.014

Data are presented as estimated mean and standard error.