Vagal Nerve Stimulation-Modulation of the Anti-Inflammatory Response and Clinical Outcome in Psoriatic Arthritis or Ankylosing Spondylitis

Table 3

Results—ankylosing spondylitis.

	Baseline	20 min	value	Day 2	value	Day 5	value	Overall value
Cardiometric data
Cardiac vagal tone (LVS)	5.59 (0.77)	6.56 (0.77)	0.014	5.75 (0.77)	0.692	5.22 (0.77)	0.361	0.008
Heart rate (bpm)			0.009		0.401		0.796	0.041
Systolic BP (mmHg)			0.822		0.565		0.920	0.861
Diastolic BP (mmHg)			0.900		0.616		0.900	0.911
Disease activity
DAS28-CRP	1.78 (0.17)	-	-	1.76 (0.17)	0.598	1.77 (0.17)	0.845	0.868
ASDAS	1.75 (0.21)	-	-	1.66 (0.21)	0.128	1.67 (0.21)	0.139	0.220
CRP (mg/L)	3.02 (0.88)	-	-	3.08 (0.88)	0.784	3.09 (0.88)	0.211	0.408
Cytokines
IFN-γ (pg/L)	4.36 (0.95)	-	-	3.76 (0.95)	0.017	4.44 (0.95)	0.440	0.055
IL-8 (pg/mL)	3.83 (0.33)	-	-	3.03 (0.35)	0.024	3.90 (0.33)	0.840	0.026
IL-10 (pg/mL)	0.46 (0.05)	-	-	0.42 (0.05)	0.008	0.44 (0.05)	0.090	0.024
TNF-α (pg/mL)	1.43 (0.19)	-	-	1.44 (0.19)	0.861	1.51 (0.19)	0.167	0.331

Data are presented as estimated mean and standard error.