Identifying Macrophage-Related Genes in Ulcerative Colitis Using Weighted Coexpression Network Analysis and Machine Learning

Figure 6

Diagnostic value and expression of three candidate genes. Expression of SLC6A14, HMGCS2, and ENPP1 in UC and control tissues in GSE87473 (a) and in tissues from GSE38713 (b). Expression of candidate diagnostic markers before and after treatment in infliximab treatment responders in GSE16879 (c) and GSE23597 (d). (e) ROC curves for four machine learning classifiers based on three candidate diagnostic markers in the training set GSE87473 and test set GSE38713. (f) ROC curves for identifying activate UC based on three candidate diagnostic markers in the metacohort and GSE38713.

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