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No. | Gene symbol | Full name | Function |
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1 | PTPRC | Encoding protein-tyrosine phosphatase receptor-type C | PTPRC is one of the most abundant leukocyte cell surface glycoproteins and is expressed exclusively upon cells of the hematopoietic system |
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2 | TYROBP | Transmembrane immune signaling adaptor TYROBP | The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element |
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3 | FCGR3A | Fc gamma receptor IIIa | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen–antibody complexes from the circulation |
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4 | ITGAX | Integrin subunit alpha X | This gene encodes the integrin alpha X chain protein |
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5 | LCP2 | Lymphocyte cytosolic protein 2 | Participates in immune response and intracellular signal transduction |
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6 | IL1B | Interleukin 1 beta | This cytokine is an important mediator of the inflammatory response and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis |
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7 | IRF8 | Interferon regulatory factor 8 | Plays critical roles in interferon (IFN) signaling pathways governing the establishment of innate immune responses by myeloid and dendritic cells |
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8 | LILRB2 | Leukocyte immunoglobulin-like receptor B2 | Control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity |
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9 | CD68 | CD68 molecule | Clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages |
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10 | C1QB | Complement C1q B chain | Plays an important role in maintaining the stability of the body’s environment, oxidative stress, glucose and lipid metabolism, and other processes |
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11 | CCR7 | C–C motif chemokine receptor 7 | This receptor was identified as a gene induced by the Epstein–Barr virus (EBV), controls the migration of memory T cells to inflamed tissues, as well as stimulates dendritic cell maturation |
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12 | C1QA | Complement C1q A chain | Plays an important role in maintaining the stability of the body’s environment, oxidative stress, glucose and lipid metabolism, and other processes |
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