Research Article
Potential Association of the Oral Microbiome with Trimethylamine N-Oxide Quantification in Mexican Patients with Myocardial Infarction
Table 1
Summary of cohort characteristics.
| | Total (N = 16) | Without risk factor (N = 6) | Risk factor (N = 10) | p Value |
| Trimethylamine N-oxide (nmol/mL)a | 0.86 (0.53–1.45) | 0.94 (0.79–1.66) | 0.84 (0.33–1.25) | 0.588 | Age (years) | 61 (36–78) | 67 (48–78) | 59 (36–70) | 0.302 | Men, n (%) | 15 (93.7) | 5/6 | 10/10 | 0.375 | Patient medical history | Diabetes, n (%) | 5 (31.2) | Non | 5 (50) | | Hypertension, n (%) | 7 (43.7) | Non | 7 (70) | | Dyslipidemia, n (%) | 3 (18.7) | Non | 3 (30) | | Current smoking, n (%) | 4 (25) | Non | 4 (40) | | Clinical features | Killip–Kimball > 2 | 3 (18.7) | Non | 3 (30) | 0.25 | MACE, n (%) | 4 (25) | Non | 4 (40) | 0.234 | TIMI ≥ 2n (%) | 10 (62.5) | 3 (50) | 7 (70) | 0.607 | Affected blood vessels ≥ 2n (%) | 11 (68.7) | 3 (50) | 8 (80) | 0.299 | Anterior descending, n (%) | 13 (81.2) | 3 (50) | 10 (100) | | Circumflex, n (%) | 8 (50) | 3 (50) | 5 (50) | 1.000 | Right coronary, n (%) | 11 (68.7) | 4 (66.7) | 7 (70) | 1.000 | Body mass indexa | 26.9 (25.6–28.7) | 28.6 (27.0–32.9) | 26.5 (25.2–27.8) | 0.221 | Biochemical markers | cTnI (ng/mL)a | 32.9 (4.25–260.9) | 441.8 (23.7–4101.0) | 11.8 (2.3–69.6) | | Total cholesterol (mg/dL)a | 164.1 (133.3–175.3) | 179.3 (159.5–232.3) | 152.4 (131.0–165.0) | 0.104 | HDL (mg/dL)a | 35.5 (28.5–43.3) | 31.5 (31.4–38.3) | 35.5 (28.2–50.2) | 0.664 | LDL (mg/dL)a | 94.9 (88.0–124.9) | 137.2 (112.5–171.1) | 91.9 (86.4–95.6) | | Triglycerides (mg/dL)a | 138.5 (112.7–170.8) | 131.5 (112.7–170.3) | 143.1 (97.1–182.0) | 0.958 | Atherogenic indexa | 3.05 (2.4–4.3) | 4.5 (3.4–4.89) | 2.6 (1.9–3.09) | | Glucose (mg/dL) | 127 (115.5–157.5) | 125 (116.0–136.0) | 129 (115.0–212.0) | 0.786 |
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aMedian (IQR), p value Mann–Whitney or Fisher’s exact test. MACE: major adverse cardiovascular event, TIMI: thrombolysis in myocardial infarction score. cTnI: cardiac troponin I, HDL: high-density protein, LDL: low-density protein. . |