Salvianolic Acid B Alleviates High Glucose-Induced Vascular Smooth Muscle Cell Inflammation by Upregulating the miR-486a-5p Expression

Figure 1

Sal B attenuates vascular inflammation in diabetic mice. (a) The chemical structure of Sal B. (b, c) The concentrations of IL-1β and TNF-α in mice serum were detected by ELISA. vs. DM group (n = 7). (d) qRT-PCR measured the IL-1β and TNF-α expression in mice aortic vessels. Relative mRNA expression was presented after normalizing to GAPDH (means ± SEM, n = 7). vs. DM group. (e) The IL-1β and TNF-α expression in mice aortic vessels was measured by western blot analysis (left panel). Bar graphs show the relative level of these proteins for three independent experiments. vs. DM group (right panel, n = 7).

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