Correlation between the Systemic Immunoinflammatory Index and Platelet–Lymphocyte Ratio in Patients with Adenomyosis

Table 1

Baseline characteristics of included patient by SII quartile.

Characteristic	SII (min–max)				P value
	Q1 (118.33–403.04)	Q2 (403.50–571.32)	Q3 (575.96–841.21)	Q4 (842.00–2933.89)
N	116	123	124	120
Age (years, mean ± SD)	46.53 ± 5.65	46.41 ± 5.65	46.54 ± 5.75	46.09 ± 5.59	0.921
Gravidity (n)	3 (0–9)	3 (1–8)	3 (0–8)	3 (0–9)	0.059
Parity (n)	2 (0–4)	2 (1–5)	2 (0–4)	2 (0–4)	0.176
Gravidity (n, %)					0.515
0	1 (0.86%)	0 (0.00%)	4 (3.23%)	2 (1.67%)
1	8 (6.90%)	8 (6.50%)	10 (8.06%)	8 (6.67%)
2 and more	107 (92.24%)	115 (93.50%)	110 (88.71%)	110 (91.67%)
Parity (n, %)					0.016
0	1 (0.86%)	0 (0.00%)	7 (5.65%)	3 (2.50%)
1	54 (46.55%)	47 (38.21%)	48 (38.71%)	38 (31.67%)
2 and more	61 (52.59%)	76 (61.79%)	69 (55.65%)	79 (65.83%)
BMI (kg/m^2, mean ± SD)	24.70 ± 3.11	27.79 ± 26.88	25.16 ± 3.15	24.74 ± 3.34	0.248
Menstrual regularity, n (%)					0.362
Regular	111 (95.69%)	114 (92.68%)	120 (96.77%)	111 (92.50%)
Irregular	5 (4.31%)	9 (7.32%)	4 (3.23%)	9 (7.50%)
Dysmenorrhea, n (%)					0.416
No	57 (49.14%)	61 (49.59%)	50 (40.32%)	58 (48.33%)
Yes	59 (50.86%)	62 (50.41%)	74 (59.68%)	62 (51.67%)
Menstrual volume					0.019
Low	5 (4.31%)	2 (1.63%)	4 (3.23%)	1 (0.83%)
Moderate	80 (68.97%)	80 (65.04%)	74 (59.68%)	61 (50.83%)
High	31 (26.72%)	41 (33.33%)	46 (37.10%)	58 (48.33%)
Hypertension, n (%)					0.217
No	100 (86.21%)	112 (91.06%)	106 (85.48%)	111 (92.50%)
Yes	16 (13.79%)	11 (8.94%)	18 (14.52%)	9 (7.50%)
Diabetes, n (%)					0.025
No	116 (100.00%)	123 (100.00%)	119 (95.97%)	118 (98.33%)
Yes	0 (0.00%)	0 (0.00%)	5 (4.03%)	2 (1.67%)
Endometriosis, n (%)					0.416
No	100 (86.21%)	103 (83.74%)	97 (78.23%)	98 (81.67%)
Yes	16 (13.79%)	20 (16.26%)	27 (21.77%)	22 (18.33%)
Benign adnexal tumor, n (%)					0.076
No	68 (58.62%)	63 (51.22%)	80 (64.52%)	60 (50.00%)
Yes	48 (41.38%)	60 (48.78%)	44 (35.48%)	60 (50.00%)
Uterine leiomyoma					0.897
No	49 (42.24%)	53 (43.09%)	49 (39.52%)	53 (44.17%)
Yes	67 (57.76%)	70 (56.91%)	75 (60.48%)	67 (55.83%)
Uterine adenomyoma					0.356
No	85 (73.28%)	100 (81.30%)	96 (77.42%)	98 (81.67%)
Yes	31 (26.72%)	23 (18.70%)	28 (22.58%)	22 (18.33%)
Menopause					<0.001
No	104 (89.66%)	117 (95.12%)	123 (99.19%)	120 (100.00%)
Yes	12 (10.34%)	6 (4.88%)	1 (0.81%)	0 (0.00%)
Anaemia					<0.001
Normal	67 (57.76%)	46 (37.40%)	42 (33.87%)	23 (19.17%)
Mild	27 (23.28%)	41 (33.33%)	36 (29.03%)	39 (32.50%)
Moderate	21 (18.10%)	34 (27.64%)	40 (32.26%)	52 (43.33%)
Severe	1 (0.86%)	2 (1.63%)	6 (4.84%)	6 (5.00%)
Uterine volume (cm^3)	184.79 ± 129.50	193.84 ± 108.61	220.21 ± 170.14	241.00 ± 150.91	0.009
Length (cm)	7.09 ± 1.81	7.20 ± 1.45	7.38 ± 1.78	7.72 ± 1.81	0.028
Width (cm)	6.92 ± 1.77	7.07 ± 1.44	7.35 ± 1.84	7.61 ± 1.68	0.010
Thickness (cm)	6.21 ± 1.65	6.58 ± 1.51	6.66 ± 1.71	6.95 ± 1.62	0.006
Hemoglobin	112.66 ± 21.93	102.41 ± 21.74	100.09 ± 25.61	90.39 ± 20.49	<0.001
Platelet (10^9/L, mean ± SD)	241.68 ± 53.80	281.20 ± 62.26	307.72 ± 76.08	354.57 ± 94.31	<0.001
Neutrophil (10^9/L, mean ± SD)	2.75 ± 0.89	3.23 ± 0.97	4.07 ± 1.06	5.46 ± 2.16	<0.001
Lymphocyte (10^9/L, mean ± SD)	2.10 ± 0.57	1.85 ± 0.54	1.79 ± 0.59	1.47 ± 0.41	<0.001
SII (mean ± SD)	312.77 ± 68.19	480.99 ± 46.65	694.64 ± 77.47	1306.82 ± 468.09	<0.001
PLR (mean ± SD)	120.84 ± 34.71	161.07 ± 48.00	181.17 ± 46.56	255.46 ± 85.26	<0.001