AEBP1 Is One of the Epithelial-Mesenchymal Transition Regulatory Genes in Colon Adenocarcinoma

Figure 2

AEBP1 is highly associated with EMT in COAD patients. (a) Heatmap analysis showed AEBP1 expression and the levels of EMT biomarkers (SNAI1, SNAI2, TWIST1, ZEB1, ZEB2, CDH1, CDH2, VIM, MMP2, MMP3, MMP9, KRT8, and TJP1) in 329 COAD patients. The high mRNA levels of AEBP1 were positively associated with EMT metagene scores and the expression of EMT-related genes. (b) Correlation between AEBP1 expression and the levels of EMT biomarkers (SNAI1, SNAI2, TWIST1, ZEB1, ZEB2, CDH1, CDH2, VIM, MMP2, MMP3, MMP9, KRT8, and TJP1) in 329 COAD patients.

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