Spectral Photon-Counting Molecular Imaging for Quantification of Monoclonal Antibody-Conjugated Gold Nanoparticles Targeted to Lymphoma and Breast Cancer: An <i>In Vitro</i> Study

<div>(a) Linearity of attenuation of calibration vials containing AuNP for each energy bin. <i>R</i><sup>2</sup> = 0.99 for all linearity trends. (b) Spectral response of the detector for calibration vials. Enhancement of attenuation due to K-edge observed in energy bin 4 (75–118 keV). Insets show material decomposed images corresponding to each concentration. (c) and (d) Spectral response of Raji and SKBR3 cells, respectively. Standard errors are shown for spectral response data.</div>

Contrast Media & Molecular Imaging

fig2

Figure 2

Figure 2: Spectral Photon-Counting Molecular Imaging for Quantification of Monoclonal Antibody-Conjugated Gold Nanoparticles Targeted to Lymphoma and Breast Cancer: An <i>In Vitro</i> Study 

Figure 2 | Spectral Photon-Counting Molecular Imaging for Quantification of Monoclonal Antibody-Conjugated Gold Nanoparticles Targeted to Lymphoma and Breast Cancer: An In Vitro Study 