Combined Volumetric and Density Analyses of Contrast-Enhanced CT Imaging to Assess Drug Therapy Response in Gastroenteropancreatic Neuroendocrine Diffuse Liver Metastasis

<div>The tumor volume and HU histogram changes in one of the cases. Gastroenteropancreatic neuroendocrine liver metastasis pre- and posttreatment illustrating total tumor volume and mean volumetric tumor density changes from contrast-enhanced CT images in a patient with tumor regression. GEP-NETs with liver metastasis pretreatment (a) show a pretreatment tumor volume of 57.4 cm<sup>3</sup>, whereas in (b) the posttreatment, tumor volume was 40.9 cm<sup>3</sup>. The HU histogram (c) shows a left side shift, representing decreased enhancement in the posttreatment CT imaging, that is, HU value decreased from 80.2 to 68.1 HU.</div>

Contrast Media & Molecular Imaging

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Figure 2: Combined Volumetric and Density Analyses of Contrast-Enhanced CT Imaging to Assess Drug Therapy Response in Gastroenteropancreatic Neuroendocrine Diffuse Liver Metastasis 

Figure 2 | Combined Volumetric and Density Analyses of Contrast-Enhanced CT Imaging to Assess Drug Therapy Response in Gastroenteropancreatic Neuroendocrine Diffuse Liver Metastasis 