¹¹C-Labeled Pictilisib (GDC-0941) as a Molecular Tracer Targeting Phosphatidylinositol 3-Kinase (PI3K) for Breast Cancer Imaging

Figure 3

(a) Analytic HPLC chromatograms after the coinjection of [¹¹C]-pictilisib (retention time = 14.05 min) and reference standard GDCI (UV 254 nm); (b)–(d) [¹¹C]-pictilisib stability in human serum after incubation at 37°C for 30 min, 60 min, and 90 min, respectively.

(a)

(b)

(c)

(d)