Visualizing the Distribution of Matrix Metalloproteinases in Ischemic Brain Using In Vivo ¹⁹F-Magnetic Resonance Spectroscopic Imaging

Figure 2

¹⁹F-MRSI of MMPs intracranially administered in the MMP2 knockout mice brain. MRSI color images were coregistered and superimposed with T₂-weighted ¹H-MRI. (a) Pro-MMP9, (b) activated MMP9, (c) pro-MMP2, or (d) pro-MMP3 was administered at 30 min before intravenous administration of TGF-019.

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