Research Article
Evaluation of Myelin Radiotracers in the Lysolecithin Rat Model of Focal Demyelination: Beware of Pitfalls!
Figure 3
In vivo PET imaging with [11C]PIB. T2WI MRI is shown in the left column and overlaid with a 20 min summed PET image of [11C]PIB in the right column. Rats A and B (a, b) exhibited a large demyelination area without necrosis or ventricle dilation. Rats C and D (c, d) presented a smaller demyelination area and necrosis (c) or ventricle dilation (d).
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