In Vivo Evaluation of Gallium-68-Labeled IRDye800CW as a Necrosis Avid Contrast Agent in Solid Tumors

Figure 2

In vitro dead cell binding of [68Ga]Ga-DOTA-PEG4-IRDye800CW ([68Ga]Ga-1) and [68Ga]Ga-EDTA ([68Ga]Ga-2). (a, c) Dead or alive 4T1-Luc2 cells in a 12-well plate, treated with either [68Ga]Ga-1 or [68Ga]Ga-2. In (a), the autoradiography signal and in (c), the corresponding 800 nm channel are represented in green. In (b), the quantification of bound radioactivity and in (d), the quantification of fluorescent signal are depicted. Error bars represent standard error of the mean. ns, no significant difference. ., .

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