Research Article

Radiomic Features of 18F-FDG PET in Hodgkin Lymphoma Are Predictive of Outcomes

Table 1

Radiomic parameters.

IndexMatrixParameter

ConventionalSUVmin, SUVmean, SUVmax, SUVpeak, and SUVStd
Advanced indicesMTV and TLG
Histogram-derived parametersSkewness, kurtosis, entropy, and energy
Shape-derived parametersSphericity and compacity
Texture featuresGLCMHomogeneity, energy, contrast, correlation, entropy, and dissimilarity
GLRLMSRE/LRE, LGRE/HGRE, SRLGE/SRHGE, LRLGE/LRHGE, GLNU/RLNU, and RP
NGLDMCoarseness, contrast, and busyness
GLZLMSZE, LZE, LGZE, HGZE, SZLGE, SZHGE, LZLGE, LZHGE, GLNU, ZLNU, and ZP

MTV: metabolic tumor volume; TLG: total lesion glycolysis; GLCM: gray-level co-occurrence matrix; GLRLM: gray-level run-length matrix; SRE/LRE: short/long-run emphasis; LGRE/HGRE: low/high gray-level run emphasis; SRLGE/SRHGE: short-run low/high gray-level emphasis; LRLGE/LRHGE: long-run low/high gray-level emphasis; GLNU/RLNU: gray-level nonuniformity/run-length nonuniformity; RP: run percentage; NGLDM: neighborhood gray-level difference matrix; GLZLM: gray-level zone-length matrix; SZE/LZE: short/long-zone emphasis; LGZE/HGZE: low/high gray-level zone emphasis; SZLGE/SZHGE: short-zone low/high gray-level emphasis; LZLGE/LZHGE: long-zone low/high gray-level emphasis; GLNU/ZLNU: gray-level nonuniformity or zone-length nonuniformity; ZP; zone percentage.