Review Article

Diagnostic Accuracy of 18F-FDG-PET/CT and MRI in Predicting the Tumor Response in Locally Advanced Cervical Carcinoma Treated by Chemoradiotherapy: A Meta-Analysis

Table 3

Patients’ pathologic and imaging characteristics.

AuthorFIGO stageHistopathologyPelvic LN metastasisPrevalence of distant metastasis3-OSDFI (month)MTVTLGPersistenceCRPFSSUVmean
IBIIA-IIBIIIA-IIIBSCCAdenocarcinomaPartial responseComplete response

Rufini et al.3 (3.4%)72 (81.7%)13 (14.7%)77 (87.5%)11 (12.5%)40 (45.5%)10 (11.4%)N/A15.533.8 (1.2–180.0)240.2 (7.9–2417.0)N/AN/AN/A2.1 (1.1–5.7)1.8 ± 0.7
Cetina et al.2/16 (12%)8/16 (50%)3/16 (19%)15/16-(94%)1 (6.2%)N/AN/AN/A14.5N/AN/AN/AN/AN/AN/AN/A
Perrone et al.N/AN/AN/A32 (80%)8 (20%)17 (42.5%)1 (2.5%)88%N/AN/AN/A8 (20%)33 (82.5%)78%7.5 ± 5.1N/A
Chen et al.37 (26%)78 (55%)27 (19%)114 (80%)28 (20%)61 (43%)27 (19%)N/AN/A28.1 ± 42.7216.1 ± 280.522 (15%)120 (84%)N/A5.12 ± 1.171.28
Choi et al.3 (1.9%)102 (75%)17 (12.4%)124 (91.2%)9 (6.6%)N/A12 (22.2%)N/AN/AN/AN/A18 (13.2%)124 (91%)N/A5.7 ± 2.62.5 ± 0.8
Oh et al.3 (5%)46 (77%)8 (13%)52 (87%)8 (13%)42 (70%)6 (10%)93.6%N/AN/AN/A4 (7%)43 (73%)71.9%N/AN/A

SCC: squamous cell carcinoma; LN: lymph node; DFI: disease-free interval; 3-OS: 3-month overall survival; MTV: metabolic tumor volume; TLG: total lesion glycolysis; CR: complete response; PFS: progression-free survival; and SUV: standardized uptake value.