Research Article

FAPI-04 Uptake in Healthy Tissues of Cancer Patients in 68Ga-FAPI-04 PET/CT Imaging

Table 1

Median, mean, minimum, and maximum SUV values of tissues and organs.

SUVmaxSUVavgSUVavg
MedianMin/maxMedianMin/maxMean/SD

Uterine corpus11.742.62–37.398.591.73–25.3210.1 ± 6.06
Renal pelvis8.481.38–995.080.99–62.999.9 ± 12.02
Uterine cervix4.311.33–9.582.9550.94–7.063.1 ± 1.42
Submandibular gland3.461.28–8.952.20.78–5.612.4 ± 1.02
Pancreatic tail30.94–8.261.820.55–5.452 ± 1
Ovaries2.690.3–5.871.7350.14–3.551.9 ± 0.86
Pancreatic corpus2.611.04–2.581.660.79–8.622.2 ± 1.52
Esophagogastric junction2.461.08–3.791.560.69–2.861.5 ± 0.45
Quadratus lumborum muscle2.380.79–7.731.690.58–4.131.7 ± 0.73
Esophagus2.341.15–9.111.710.87–3.91.8 ± 0.59
Scalp2.320.98–5.181.490.56–3.51.5 ± 0.52
Palatine tonsils2.321.14–4.681.560.7–2.761.6 ± 0.49
Prostate2.291.09–5.51.50.65–2.71.6 ± 0.67
Renal cortex2.241.22–3.731.40.73–2.331.4 ± 0.37
Pancreatic head2.221.18–10.131.4250.74–6.381.8 ± 1.24
Thyroid2.020.76–10.831.440.56–6.791.7 ± 1.19
Testis21–3.071.430.72–1.871.3 ± 0.39
Rectum1.930.74–4.961.270.44–3.021.3 ± 0.57
Abdominal aorta1.80.85–3.041.220.59–2.11.2 ± 0.35
Nasopharynx1.760.57–6.911.110.33–3.821.1 ± 0.51
Parotid gland1.750.83–3.651.190.55–2.491.3 ± 0.41
Thoracic aorta1.70.83–3.721.230.56–2.461.3 ± 0.41
Reactive lymph nodes (cervical)1.740.98–6.881.440.85–4.241.5 ± 0.69
Psoas muscle1.680.51–3.611.070.35–2.31.1 ± 0.43
Thymus1.670.96/2.171.270.72/1.581.3 ± 0.53
Lung hilum1.640.6–3.161.070.4–2.31.1 ± 0.4
Stomach corpus1.510.41–3.930.970.23–2.281 ± 0.4
Left ventricular walls1.390.6–2.590.890.41–1.770.9 ± 0.32
Stomach antrum1.380.58–4.20.90.33–2.511 ± 0.41
Breast glandular tissue1.3450.58–5.280.8150.33–3.551.2 ± 0.79
Nipple1.330.42–4.970.750.11–2.821 ± 0.61
Spleen1.2950.64–2.810.810.34–1.950.9 ± 0.33
Duodenum1.250.6–2.920.840.37–1.670.9 ± 0.31
Ileum1.2050.24–3.560.790.17–2.510.9 ± 0.47
Liver1.190.47–2.910.780.31–1.640.8 ± 0.3
Iliac bone1.1350.57–2.120.70.34–1.310.7 ± 0.21
Lung parenchyma1.130.37–2.710.770.26–1.630.8 ± 0.3
Descending colon1.10.53–2.130.70.32–1.510.7 ± 0.28
Cecum1.090.08–2.390.7050.05–1.590.7 ± 0.28
Sternum1.060.52–1.050.730.34–1.150.7 ± 0.17
Femur neck1.010.42–2.210.610.29–1.160.6 ± 0.21
Lumbar vertebrae0.990.51–2.20.650.28–1.870.7 ± 0.26
Gallbladder0.850.42–1.730.580.24–1.310.6 ± 0.27
Mesenteric adipose tissue0.7950.26–1.670.550.16–1.170.6 ± 0.27
Humeral head0.750.44–1.930.450.25–1.380.5 ± 0.24
Cerebellar cortex0.20.05–0.90.110.03–0.30.1 ± 0.07
Cerebral cortex0.080.01–0.270.030.01–0.180.0 ± 0.03
Primary tumors12.611.65–50.448.391.23–29.639.5 ± 5.87

SUV: standard uptake value, SD: standard derivation, avg: average.