Research Article

The Anion Gap and Mortality in Critically Ill Patients with Hip Fractures

Table 1

Baseline characteristics of the study population.

CharacteristicsSurvivalMortalityP value

N33164

Age, years69.6 ± 20.083.8 ± 10.0<0.001

Sex, n (%)0.008
 Male157 (47.4%)42 (65.6%)
 Female174 (52.6%)22 (34.4%)

Ethnicity, n (%)0.032
 White258 (77.9%)59 (92.2%)
 Black16 (4.8%)1 (1.6%)
 Others57 (17.2%)4 (6.2%)

Vital signs
 SBP (mmHg)118.3 ± 15.6116.2 ± 20.80.135
 DBP (mmHg)58.1 ± 10.654.2 ± 12.70.009
 MAP (mmHg)75.4 ± 10.873.2 ± 12.80.115
 Heart rate (bpm)88.7 ± 15.687.0 ± 18.00.403
 Respiratory rate (t/min)18.5 ± 3.620.7 ± 4.40.403
 Temperature (°C)36.9 ± 0.636.6 ± 0.90.027
 SpO2 (%)97.1 ± 3.696.6 ± 2.70.053

Comorbidities
 Heart failure, n (%)92 (27.8%)38 (59.4%)<0.001
 Hypertension, n (%)48 (14.5%)12 (18.8%)0.375
 Obesity, n (%)13 (3.9%)5 (7.8%)0.169
 Infection, n (%)151 (45.6%)36 (56.2%)0.109

Laboratory parameters
 AG12.3 ± 3.213.3 ± 3.5<0.001
 WBC, 109/L10.2 ± 6.111.4 ± 5.80.079
 Platelet, 109/L185.2 ± 101.4203.1 ± 118.60.524
 Hemoglobin (g/dl)9.3 ± 1.89.7 ± 1.80.094
 Hematocrit (%)27.0 ± 5.428.8 ± 5.50.005
 Creatinine (mg/dl)1.2 ± 1.11.2 ± 0.80.013
 BUN (mg/dl)23.1 ± 15.631.0 ± 17.8<0.001
 Lactate (mol/L)1.8 ± 1.12.2 ± 1.60.524

Scoring systems
 APSIII score45.7 ± 17.959.5 ± 22.2<0.001
 Length of stay in ICU4.0 ± 5.24.1 ± 4.30.626

AG, anion gap; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; ICU, intensive care unit; WBC, white blood cell; BUN, blood urea nitrogen.