Research Article

The Anion Gap and Mortality in Critically Ill Patients with Hip Fractures

Table 2

Baseline characteristics of the study population according to AG.

AGP value
<12.5≧12.5

N225170

Age, years69.5 ± 21.375.1 ± 16.00.026

Sex, n (%)0.459
 Male117 (52.0%)82 (48.2%)
 Female108 (48.0%)88 (51.8%)

Ethnicity, n (%)0.088
 White189 (84.0%)128 (75.3%)
 Black7 (3.1%)10 (5.9%)
 Others29 (12.9%)32 (18.8%)

Vital signs
 SBP (mmHg)118.2 ± 16.8117.9 ± 16.10.874
 DBP (mmHg)57.3 ± 10.457.6 ± 11.90.723
 MAP (mmHg)75.1 ± 11.274.9 ± 11.10.773
 Heart rate (bpm)89.5 ± 16.086.9 ± 16.00.129
 Respiratory rate (t/min)18.7 ± 3.919.2 ± 3.80.403
 Temperature (°C)36.9 ± 0.636.7 ± 0.70.013
 SpO2 (%)97.5 ± 2.096.4 ± 4.8<0.001

Comorbidities
 Heart failure, n (%)66 (29.3%)64 (37.6%)0.082
 Hypertension, n (%)22 (9.8%)38 (22.4%)<0.001
 Obesity, n (%)9 (4.0%)9 (5.3%)0.541
 Infection, n (%)104 (46.2%)83 (48.8%)0.608

Laboratory parameters
 WBC, 109/L9.6 ± 4.511.4 ± 7.40.010
 Platelet, 109/L178.5 ± 90.5200.7 ± 119.70.069
 Hemoglobin (g/dl)9.1 ± 1.69.6 ± 2.0<0.001
 Hematocrit (%)26.4 ± 5.028.4 ± 6.0<0.001
 Creatinine (mg/dl)0.9 ± 0.41.6 ± 1.5<0.001
 BUN (mg/dl)20.0 ± 11.730.3 ± 19.2<0.001
 Lactate (mol/L)1.7 ± 0.82.1 ± 1.50.021

Scoring systems
 APSIII score44.7 ± 17.252.3 ± 21.1<0.001
 Length of stay in ICU4.0 ± 5.24.1 ± 4.30.626
 30-day mortality28 (12.4%)36 (21.2%)0.020
 90-day mortality42 (18.7%)48 (28.2%)0.025

AG, anion gap; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; ICU, intensive care unit; WBC, white blood cell; BUN, blood urea nitrogen.