Network Pharmacology Integrated Molecular Docking to Explore the Mechanism of Blister Beetle Therapy for Lung Adenocarcinoma

Figure 4

Construction of the LUAD diagnostic model and screening of biomarkers. (a) The characteristic genes were screened by LASSO regression analysis. Deviance on the horizontal axis represents the proportion of residual explained by the model, showing the relationship between the number of characteristic genes and the proportion of residual explained by the model (Dev), and the coefficient of genes on the vertical axis (left). The x-coordinate is log (Lambda), and the y-coordinate represents the error of cross-validation (right). (b) Evaluation and validation of the diagnostic model by the ROC curve. (c, d) The cumulative residual distribution diagram of the sample (left) and the boxplot of the sample residual (right). The curve area indicates the cumulative residual value of the whole sample. The smaller the curve area is, the smaller the cumulative residual value of the sample is. The red dot represents the root mean square of the residual. (e) Importance of genetic variables in the RF models. (f) Evaluation of the RF model by the ROC curve.

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