Research Article

[Retracted] The Clinical Efficacy and Economic Benefits of Recombinant Human Thrombopoietin for the Treatment of Chemotherapy or Chemoradiotherapy-Induced Thrombocytopenia

Table 6

Comparison of indicators in the use of rhTPO for treatment of grade II and IV thrombocytopenia [n, (%)].

IndicatorsUse of recombinant human thrombopoietin (rhTPO)z/χ2 valueP value
Grade II (n = 100)Grade IV (n = 39)

Days of treatment5.00 (3.00, 6.00)6.00 (4.00, 11.00)−2.9550.003
Time to increase platelets (days)3.00 (2.00, 5.00)6.00 (3.00, 11.00)−4.235<0.001
Delay of the next chemoradiotherapy cycle (days)0 (0, 5.75)3.00 (0, 8.00)−2.2350.025
Prolonged hospitalization due to platelet decline (days)1.00 (0,6.00)5.00 (0,8.00)−2.6550.008
Increased hospitalization costs due to platelet decline5040.00 (3024.00, 6979.00)7440.00 (5874.00, 14410.00)−4.755<0.001
Platelet transfusion
 No95 (95.0)16 (41.0)50.813<0.001
 Yes5 (5.0)23 (59.0)