Research Article

RETRACTED: The Significance of PAX8-PPARγ Expression in Thyroid Cancer and the Application of a PAX8-PPARγ-Targeted Ultrasound Contrast Agent in the Early Diagnosis of Thyroid Cancer

Figure 2

PAX8-PPARγ antisense oligonucleotides induce growth inhibition and apoptosis of the thyroid cancer clonogenic growth. (a) SW579 cells were plated in 6-well culture plates in 0.7% soft agar with 0 μM and 3 μM for 21 days, and then colonies (>40 microphotographs of thyroid colonies after exposure to antisense oligonucleotides). (b) PAX8-PPARγ antisense oligonucleotide exposure decreases the plate colony formation rate of the SW579 cells. (c) Thyroid cancer cells were cultured in DMEM with 10% serum, treated with different doses (0 μ M-5 μM) of PAX8-PPARγ antisense oligonucleotides for 4 days, and then collected for the analysis of PAX8-PPARγ expression by western blot, and apoptosis with FCM.  < 0.05;  < 0.01.
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