Biliary Drainage Reduces Intestinal Barrier Damage in Obstructive Jaundice by Regulating Autophagy

Figure 3

Autophagy response of intestinal mucosal cells in rats with obstructive jaundice can be activated by intrabiliary drainage. The expression levels of autophagy-related genes were detected by RT-PCR. (a) Beclin-1 mRNA expression levels. (b) P62 mRNA expression levels. Data are expressed as means ± SEM (n = 10). Sham: no common bile duct ligation; BDL: bile duct ligation; ID: internal drainage; a: P < 0.05 vs. sham group. b: P < 0.05 vs. BDL group.

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