Biliary Drainage Reduces Intestinal Barrier Damage in Obstructive Jaundice by Regulating Autophagy

Figure 4

Effects of autophagy agonist and inhibitor on intestinal mucosal injury in obstructive jaundice model rats with biliary drainage. (a) Serum TNF-α, (b) IL-6, (c) IL-1β, and (d) DAO levels. Data are expressed as means ± SEM (n = 10). BDL: bile duct ligation; ID: internal drainage; IDR: internal drainage + rapamycin; ID3-MA: internal drainage  +  3-methyladenine. TNF-α: tumor necrosis factor-α; IL-6: interleukin-6; IL-1β: interleukin-1β; DAO: diamine oxidase. a: P < 0.05 vs. BDL group. b: P < 0.05 vs. ID group. c: P < 0.05 vs. IDR group.

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