Biliary Drainage Reduces Intestinal Barrier Damage in Obstructive Jaundice by Regulating Autophagy

Figure 5

Effects of autophagy agonist and inhibitor on autophagy in obstructive jaundice model rats with biliary drainage. RT-PCR was used to detect the expression levels of autophagy-related genes. (a) Beclin-1 mRNA expression levels. (b) LC3I mRNA expression levels. (c) P62 mRNA expression levels. BDL: bile duct ligation; ID: internal drainage; IDR: internal drainage + rapamycin; ID3-MA: internal drainage  +  3-methyladenine. a: P < 0.05 vs. BDL group. b: P < 0.05 vs. ID group. c: P < 0.05 vs. IDR group.

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