Toll-Like Receptor 4 Exacerbates <i>Mycoplasma pneumoniae</i>via Promoting Transcription Factor EB-Mediated Autophagy

<div>Autophagy promoted <i>M. pneumoniae</i>-induced inflammatory response. (a)The expression of LC3 II detected by immunofluorescence. Knockdown of TLR4 suppressed the upregulation of LC3 puncta induced by <i>M</i>. <i>pneumoniae</i>. (b)Quantification of A. (c) The protein expression of LC3 II/I, Beclin-1, and ULK1 determined by western blot. The protein expression of LC3 II/I and p62 increased the protein expression of LC3 II/I, Beclin-1, and ULK1. (d) Quantification of C. (e) The protein expression of LC3 II/I and p62 measured by western blot. <i>M. pneumoniae</i> increased the expression of LC3 II/I and p62, which was modulated by CQ. 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Figure 4

Figure 4: Toll-Like Receptor 4 Exacerbates <i>Mycoplasma pneumoniae</i>via Promoting Transcription Factor EB-Mediated Autophagy 

Contrast Media & Molecular Imaging

Toll-Like Receptor 4 Exacerbates Mycoplasma pneumoniaevia Promoting Transcription Factor EB-Mediated Autophagy

Figure 4