Research Article

[Retracted] Investigation on the Inhibitory Effect of Methotrexate on Rheumatoid Synovitis via the TLR4-NF-κB Pathway in a Rat Model

Table 2

Comparison of the expression of TLR4 and NF-κB mRNA in synovial tissues of rats in each group.

GroupTLR4 mRNANF-κB mRNA

Control group0.79 ± 0.100.98 ± 0.09
Model group4.21 ± 0.193.55 ± 0.15

Methotrexate groupLow dose3.26 ± 0.15#2.82 ± 1.29#
Medium dose2.17 ± 0.13#&1.94 ± 0.13#&
High dose1.18 ± 0.15#&@1.19 ± 0.09#&@