Comparison of Contrast-Enhanced Spectral Mammography and Contrast-Enhanced MRI in Screening Multifocal and Multicentric Lesions in Breast Cancer Patients

Figure 1

Imaging features of a 54-year-old female with left-sided MMBC. (a) Breast US indicated only an irregular solid hypoechoic mass in the left breast (triangle), which was diagnosed as BI-RADS 4C. (b) MLO position in left breast. In CESM, the LE-MG imaging indicated two masses with unclear and irregular edges in the outer upper quadrant of the breast (arrow). (c) In CESM, the RSM imaging indicated the weak and significantly heterogeneous enhancement of masses. Two masses were diagnosed as BI-RADS 4C. (d, e) The patient received CE-MRI again due to disputes in the results of the US and CESM. The MIP imaging obtained after CE-MRI at transverse and coronal views. They indicated two significantly heterogeneous enhancements of masses with spiculated edges (arrows), which were diagnosed as BI-RADS 4C. (f) The posterior mass was confirmed to be invasive lobular carcinoma after surgery. The HE staining results were observed under a magnification of 10×. (g) The anterior mass was invasive lobular carcinoma and DCIS. HE staining results were observed under a magnification of 20×.