Comparison of Contrast-Enhanced Spectral Mammography and Contrast-Enhanced MRI in Screening Multifocal and Multicentric Lesions in Breast Cancer Patients

Figure 3

Imaging features of a 45-year-old woman with MMBC in the left breast. (a) CC position in the left breast. In CESM, the LE-MG imaging indicated dense breast parenchyma with no suspicious findings. (b) In CESM, the RSM imaging indicated the first mass with irregular edge and significantly heterogeneous enhancement in the outer quadrant (arrow), which was diagnosed as BI-RADS 4C. The second and third irregular masses along the duct were seen in the inner quadrant, with mild enhancement (triangles). They were diagnosed as BI-RADS 4B. (c) US indicated a hypoechoic nodule with irregular edge (triangles), which was diagnosed as BI-RADS 4C. (d–f) T1WI image of CE-MRI fat compression in axial position showed three nodules in the left breast. The morphology and location were consistent both on CESM and CE-MRI. They were also diagnosed as BI-RADS 4C and 4B, respectively (arrows). (g) The first mass was confirmed to be IDC after surgery by HE staining under a magnification of 20×. (h) The second and third masses were DCIS, by HE staining under a magnification of 10×.